Juniper Publishers - Orbital Miasis: Complicating Squamous Cell Carcinoma Conjunctiva A Rare Case Report- JOJ Ophthalmology

Juniper Publishers - Open Access Journal of JOJ Ophthalmology 

Authored by Rayees Ahmad Sofi

Miasis refers to invasion into the living tissues of humans and other mammals by the eggs or larvae of flies from the order of Dipteria. The invasive parasitic larvae almost invariably cause massive destruction of orbital tissue especially in neglected patients accompanied by marked inflammatory reactions and secondary bacterial infections. Infestation can be caused by multiple or single larvae. We report a case of 50 yr post menopausal women who was having squamous cell carcinoma of conjunctiva and was a neglected and belonged to low socioeconomic status. The patient ultimately ended with massive orbital miasis.

Orbital miasis is very rare worldwide. Miasis is a term first introduced by F. W. Hope. Miai is a Greek word meaning ‘fly’. Miasis refers to invasion into the living tissues of humans and other mammals by the eggs or larvae of flies from the order of Dipteria [1,2]. The invasive parasitic larvae almost invariably cause massive destruction of orbital tissue especially in neglected patients accompanied by marked inflammatory reactions and secondary bacterial infections. Infestation can be caused by multiple or single larvae [3]. Nursing staff, medical and paramedic staff should be aware of this condition, particularly in high risk cases like immobile, open wound and skin malignancy patients.

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Juniper Publishers - Does Intravitreal Bevacizumab Injection for Retinopathy of Prematurity Treatment Arrest Anterior Segment Development? - JOJ Ophthalmology

Juniper Publishers - Open Access Journal of JOJ Ophthalmology 

Authored by Joobin Khadamy

Purpose: To determine intravitreal bevacizumab (IVB) effect on ocular development by comparing refractive and biometric outcomes of intravitreal bevacizumab (IVB) and laser photocoagulation for treatment of retinopathy of prematurity (ROP).

Methods: A prospective nonrandomized interventional comparative study was conducted in a referral hospital for ROP management. All patients who received either single IVB or diode laser photocoagulation were enrolled. Cycloplegic refraction and biometry was performed before treatment and at the corrected age of 9 months.

Results: The IVB group included 17 patients (28 eyes; gestational age (GA): 28.54 ±2.2 weeks) and the laser group included 17 patients (34 eyes; GA: 28.53 ± 1.6 w). GA, BW and corrected age at the end of follow-up was statistically similar between the two groups. Eyes in IVB group had significantly longer axial lengths and thinner lenses at final visit (p=.037 and p=.002).

Conclusions: Following IVB treatment of ROP, eye development in general and crystalline lens in particular are less affected compared to laser treatment. This supports the idea that anterior segment arrest which was first described for laser therapy of ROP occurs minimally with IVB if at all.

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